hrp0094p2-121 | Diabetes and insulin | ESPE2021

The effect of glycemic variability on DNA damage in pediatric patients with type 1 Diabetes Mellitus

Gokmen Gokhan , Altincik Ayca , Kılıc Erkek Ozgen , Tunc Ata Melek , Kılınc Toprak Emine , Kucukatay Vural , Ozhan Bayram ,

Increased glycemic variability is an important risk factor in terms of complications independent of HbA1c. The aim of this study was; to investigate the relationship between continuous glucose monitoring system (CGMS) indices and clinical data, to investigate DNA damage in patients with diabetes and to evaluate the effect of glycemic variability on DNA damage. Fifty patients with T1DM, aged under 18 years old, who were followed up at least one year in Pediatric Endocrinology D...